Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.91 |
| ▸ | TNNC1 | P63316 | 6/20 | 0.91 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.91 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.91 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.91 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.91 |
| ▸ | GPR183 | P32249 | 1/20 | 0.91 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.91 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.72 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.72 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.68 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.65 |
| ▸ | RARB | P10826 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | RARA | P10276 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5399738 | 1.00 | S1PR1 (0.91) | S1PR1TNNC1S1PR4S1PR3S1PR5 | |
| SCHEMBL6529926 | 1.00 | S1PR1 (0.91) | S1PR1TNNC1S1PR4S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL6240646 | 0.98 | S1PR1 (0.91) | S1PR1TNNC1S1PR4S1PR3S1PR5 | |
| SCHEMBL6502901 | 0.98 | S1PR1 (0.88) | S1PR1TNNC1S1PR4S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL6529334 | 0.97 | S1PR1 (0.88) | S1PR1TNNC1S1PR4S1PR3S1PR5 | |
| SCHEMBL3390328 | 0.95 | S1PR1 (1.00) | S1PR1TNNC1S1PR4S1PR3S1PR5 | |
| SCHEMBL3394797 | 0.95 | S1PR1 (1.00) | S1PR1TNNC1S1PR4S1PR3S1PR5 | |
| Fingolimod SCHEMBL7445 | 0.95 | S1PR1 (1.00) | S1PR1TNNC1S1PR4S1PR3S1PR5 | |
| SCHEMBL3392313 | 0.95 | S1PR1 (1.00) | S1PR1TNNC1S1PR4S1PR3S1PR5 | |
| SCHEMBL1372656 | 0.95 | S1PR1 (1.00) | S1PR1TNNC1S1PR4S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | claimed |