Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.38 |
| ▸ | SLC13A5 | Q86YT5 | 4/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500410 | 0.90 | ACACB (0.42) | S1PR1NPC1TP53GAAMAPT | |
| SCHEMBL6529691 | 0.87 | SLC13A5 (0.43) | SLC13A5FFAR1S1PR1S1PR3BCL2 | |
| SCHEMBL6530994 | 0.86 | S1PR1 (0.43) | SLC13A5S1PR1S1PR3BCL2 | |
| SCHEMBL6528902 | 0.85 | MMP3 (0.38) | SLC13A5FFAR1BCL2 | |
| SCHEMBL6502428 | 0.83 | FFAR1 (0.44) | SLC13A5FFAR1PPARD | |
| SCHEMBL6529918 | 0.82 | SLC13A5 (0.45) | SLC13A5NR1H4 | |
| SCHEMBL6527018 | 0.80 | RARB (0.41) | S1PR1S1PR3MAPT | |
| SCHEMBL6530516 | 0.79 | SLC13A5 (0.53) | SLC13A5S1PR1S1PR3NR1H4ACACB | |
| SCHEMBL6502451 | 0.77 | S1PR1 (0.45) | CTSAFFAR1S1PR1S1PR3MAPT | |
| SCHEMBL6531951 | 0.77 | GRM2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |