SCHEMBL6528567

SCHEMBL6528567

COC(=S)NCc1cn(-c2ccc(N3CCNCC3)c(F)c2)nn1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MIF P14174 3/20 0.42
NOTUM Q6P988 1/20 0.41
RXRA P19793 12/20 0.39
GRIN1 Q05586 12/20 0.39
GRIN2B Q13224 12/20 0.39
F10 P00742 1/20 0.38
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
CA4 P22748 1/20 0.37
CA7 P43166 1/20 0.37
KCNH2 Q12809 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
CA12 O43570 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5624221 0.89 MAOA (0.43) MIFNOTUMRXRAGRIN1GRIN2B
SCHEMBL6528899 0.88 MIF (0.40) MIFNOTUMRXRAGRIN1GRIN2B
SCHEMBL5624086 0.88 MAOB (0.46) MIFNOTUMRXRAGRIN1GRIN2B
SCHEMBL6527406 0.88 MIF (0.37) MIFNOTUMRXRAGRIN1GRIN2B
SCHEMBL14527196 0.87 NOTUM (0.41) MIFNOTUMRXRAGRIN1GRIN2B
SCHEMBL5625779 0.87 NOTUM (0.43) MIFNOTUMRXRAGRIN1GRIN2B
SCHEMBL14527052 0.86 NOTUM (0.40) MIFNOTUMRXRAGRIN1GRIN2B
SCHEMBL14527055 0.86 NOTUM (0.40) MIFNOTUMRXRAGRIN1GRIN2B
SCHEMBL14527053 0.86 NOTUM (0.42) MIFNOTUMRXRAGRIN1GRIN2B
SCHEMBL6528013 0.85 NOTUM (0.46) MIFNOTUMCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005082892-A2 TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM DR. REDDY'S LABORATORIES LTD. (IN) 2005-09-09 WO disclosed