Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 19/20 | 0.63 |
| ▸ | MAP2K2 | P36507 | 11/20 | 0.63 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5623631 | 0.96 | MAP2K1 (0.68) | MAP2K1MAP2K2 | |
| SCHEMBL5623007 | 0.88 | MAP2K1 (0.79) | MAP2K1MAP2K2IDO1 | |
| SCHEMBL6529013 | 0.86 | MAP2K1 (0.56) | MAP2K1MAP2K2 | |
| SCHEMBL6533636 | 0.84 | MAP2K1 (0.68) | MAP2K1MAP2K2 | |
| SCHEMBL6531054 | 0.83 | MAP2K1 (0.91) | MAP2K1MAP2K2IDO1 | |
| SCHEMBL6533701 | 0.82 | MAP2K1 (0.64) | MAP2K1MAP2K2 | |
| SCHEMBL5624095 | 0.80 | MAP2K1 (0.54) | MAP2K1MAP2K2 | |
| SCHEMBL6530329 | 0.79 | MAP2K1 (0.92) | MAP2K1MAP2K2 | |
| SCHEMBL6505756 | 0.78 | MAP2K1 (0.73) | MAP2K1MAP2K2 | |
| SCHEMBL5622913 | 0.78 | MAP2K1 (1.00) | MAP2K1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000818-A1 | 5-SUBSTITUTED-4-`(SUBSTITUTED PHENYL)!AMINO!-2-PYRIDONE DEVIATIVES FOR USE AS MEK INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2005-01-06 | — | — | WO | disclosed |