Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5622895 | 0.91 | MAP2K1 (0.61) | MAP2K1MAP2K2 | |
| SCHEMBL5623631 | 0.90 | MAP2K1 (0.68) | MAP2K1MAP2K2 | |
| SCHEMBL6505710 | 0.87 | MAP2K1 (0.57) | MAP2K1MAP2K2 | |
| SCHEMBL6528655 | 0.86 | MAP2K1 (0.63) | MAP2K1MAP2K2 | |
| SCHEMBL5624190 | 0.81 | MAP2K2 (0.50) | MAP2K1MAP2K2 | |
| SCHEMBL3873690 | 0.81 | TP53 (0.49) | MAP2K1MAP2K2 | |
| SCHEMBL5623906 | 0.81 | THRB (0.49) | MAP2K1MAP2K2 | |
| SCHEMBL5624185 | 0.80 | MAP2K2 (0.47) | MAP2K1MAP2K2 | |
| SCHEMBL6533636 | 0.79 | MAP2K1 (0.68) | MAP2K1MAP2K2 | |
| SCHEMBL6317553 | 0.79 | MAP2K1 (0.61) | MAP2K1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000818-A1 | 5-SUBSTITUTED-4-`(SUBSTITUTED PHENYL)!AMINO!-2-PYRIDONE DEVIATIVES FOR USE AS MEK INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2005-01-06 | — | — | WO | disclosed |