SCHEMBL652873

SCHEMBL652873

Cn1ccc(O)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1768217 0.69
SCHEMBL19204571 0.69
Hydrochloric Acid SCHEMBL13386456 0.67 CA12 (0.57)
SCHEMBL4910334 0.67
SCHEMBL6628483 0.65
SCHEMBL5951421 0.65
SCHEMBL28276651 0.65
SCHEMBL11726606 0.65 AKR1B1 (0.42)
SCHEMBL4912649 0.65
SCHEMBL4906012 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 353 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250144226-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2025-05-08 US claimed
EP-4319788-A1 REGULATION OF CELLS AND ORGANISMS Tets, Victor (US) 2024-02-14 EP claimed
WO-2022214966-A1 REGULATION OF CELLS AND ORGANISMS TETS VICTOR (US) 2022-10-13 WO claimed
US-20210283265-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2021-09-16 US claimed
EP-3774773-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. (US) 2021-02-17 EP claimed
WO-2019200161-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE DESIGN THERAPEUTICS INC. (US) 2019-10-17 WO claimed
US-10357478-B2 Polyamide compound and pharmaceutical composition for treating mitochondrial genetic diseases TRIPLEX THERAPEUTICS INC. (JP) 2019-07-23 US claimed
CN-109535133-A Pyrrole-imidazole class heterocycle polypeptide, the drug comprising pyrrole-imidazole class heterocycle polypeptide and application 深圳先进技术研究院 2019-03-29 CN claimed
CN-108236603-A A kind of Allercur polyamide liposome and preparation method thereof and application thereof 深圳先进技术研究院 2018-07-03 CN claimed
US-20170071912-A1 Polyamide Compound and Pharmaceutical Composition for Treating Mitochondrial Genetic Diseases TRIPLEX THERAPEUTICS INC. (JP) 2017-03-16 US claimed
US-6958240-B1 Inhibition of major groove DNA binding proteins by modified polyamides CALIFORNIA INSTIUTE OF TECHNOLOGY (US) 2005-10-25 US claimed
WO-2005033077-A1 SEQUENCE SELECTIVE PYRROLE AND IMIDAZOLE POLYAMIDE METALLOCOMPLEXES UNIVERSITY OF WESTERN SYDNEY (AU) 2005-04-14 WO claimed
WO-2004083365-A2 COMPOUNDS AND THEIR USE FOR SPECIFIC AND SIMULTANEOUS INHIBITION OF GENES INVOLVED IN DISEASES AND RELATED DRUGS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2004-09-30 WO claimed
EP-1307470-A2 LINKED, SEQUENCE-SPECIFIC DNA-BINDING MOLECULES UNIVERSITE DE GENEVE (CH) 2003-05-07 EP claimed
WO-2002095022-A2 SEQUENCE-SPECIFIC DNA BINDING COMPOUNDS AND THEIR USE IN TARGETING TELOMERES AND OTHER DNA SEQUENCES UNIVERSITE DE GENEVE (CH) 2002-11-28 WO claimed
US-20020169296-A1 Linked, sequence-specific DNA-binding molecules UNIVERSITE DE GENEVE (CH) 2002-11-14 US claimed
US-6472537-B1 POLYMERS FROM PRIMARY AMINE AND CARBOXYLIC ACID SUBSTITUTED PYROLE, HYDROXYPYROLE AND IMIDAZOLE MONOMERS AND HAVING 4-AMINOBUTYRIC ACID LINKER FORMING HAIRPIN TURNS AND OPTION-ALLY AMINO ACID RESIDUES; BINDING TO SPECIFIC CALIFORNIA INSTITUTE OF TECHNOLOGY 2002-10-29 US claimed
WO-2002004476-A2 LINKED, SEQUENCE-SPECIFIC DNA-BINDING MOLECULES UNIVERSITE DE GENEVE (CH) 2002-01-17 WO claimed
EP-1162961-A2 REGULATION OF HER2/neu ONCONGENE EXPRESSION BY SYNTHETIC POLYAMIDES The Scripps Research Institute (US) 2001-12-19 EP claimed
WO-2000015209-A2 REGULATION OF HER2/neu ONCONGENE EXPRESSION BY SYNTHETIC POLYAMIDES THE SCRIPPS RESEARCH INSTITUTE (US) 2000-03-23 WO claimed