Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529490 | 0.76 | CYP3A4 (0.60) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL3201746 | 0.69 | HTR6 (1.00) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL947398 | 0.64 | HTR6 (0.59) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL947354 | 0.64 | HTR6 (0.85) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL3202386 | 0.64 | HTR6 (1.00) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL4772641 | 0.63 | HTR6 (0.69) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL947230 | 0.63 | HTR6 (0.69) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL946272 | 0.63 | HTR6 (0.69) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL741573 | 0.63 | HTR6 (0.49) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL13257974 | 0.63 | HTR6 (0.53) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005066157-A1 | 3-(PYROLIDIN-3-L) INDOLES AS 5-HT6 RECEPTOR MODULATORS | SUVEN LIFE SCIENCES (IN) | 2005-07-21 | — | — | WO | disclosed |