Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527924 | 0.92 | FFAR1 (0.54) | FFAR1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL6528953 | 0.90 | FFAR1 (0.51) | FFAR1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL6528289 | 0.81 | FFAR1 (0.63) | FFAR1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL6530453 | 0.78 | FFAR1 (0.62) | FFAR1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL19131309 | 0.75 | NPC1 (0.74) | FFAR1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL6529517 | 0.75 | FFAR1 (0.57) | FFAR1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL6529240 | 0.71 | PPARG (0.60) | FFAR1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL6504738 | 0.71 | FFAR1 (0.59) | FFAR1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL6530450 | 0.69 | PPARG (0.55) | FFAR1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL5829312 | 0.68 | PPARA (0.58) | FFAR1NPC1CASP3RAB9ASENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |