Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.55 |
| ▸ | PPARA | Q07869 | 5/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529240 | 0.91 | PPARG (0.60) | PPARGPPARAFFAR1TP53NPC1 | |
| SCHEMBL6530453 | 0.90 | FFAR1 (0.62) | PPARGPPARAFFAR1TP53NPC1 | |
| SCHEMBL6529517 | 0.83 | FFAR1 (0.57) | PPARGPPARAFFAR1TP53NPC1 | |
| SCHEMBL6529794 | 0.82 | PPARG (0.59) | PPARGPPARAFFAR1 | |
| SCHEMBL6528289 | 0.80 | FFAR1 (0.63) | PPARGPPARAFFAR1NPC1RAB9A | |
| SCHEMBL6528953 | 0.80 | FFAR1 (0.51) | FFAR1TP53NPC1RAB9ACASP3 | |
| SCHEMBL6527206 | 0.72 | FFAR1 (0.61) | PPARGPPARAFFAR1NPC1RAB9A | |
| SCHEMBL6527202 | 0.72 | FFAR1 (0.61) | PPARGPPARAFFAR1NPC1RAB9A | |
| SCHEMBL6530452 | 0.72 | PPARG (0.47) | PPARGPPARAFFAR1TP53PPARD | |
| SCHEMBL6504738 | 0.71 | FFAR1 (0.59) | PPARGPPARAFFAR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | claimed |
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |