Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1481515 | 1.00 | TLR8 (0.44) | TLR8HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL1481511 | 1.00 | TLR8 (0.44) | TLR8HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL6529126 | 1.00 | TLR8 (0.44) | TLR8HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL1481804 | 0.87 | MEN1 (0.44) | TLR8HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL1481807 | 0.87 | MEN1 (0.44) | TLR8HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL1481444 | 0.85 | NPC1 (0.43) | TLR8HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL1481442 | 0.85 | NPC1 (0.43) | TLR8HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL1480504 | 0.85 | ALDH1A1 (0.44) | TLR8MAPTKDM4ERAB9AALDH1A1 | |
| SCHEMBL6532905 | 0.85 | ALDH1A1 (0.44) | TLR8MAPTKDM4ERAB9AALDH1A1 | |
| SCHEMBL1480499 | 0.85 | ALDH1A1 (0.44) | TLR8MAPTKDM4ERAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071447-A9 | SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS | TRANSTECH PHARMA INC (US) | 2005-10-13 | — | — | WO | disclosed |