Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 11/20 | 0.78 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.53 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.53 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.53 |
| ▸ | GPR183 | P32249 | 1/20 | 0.53 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.53 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6507340 | 0.99 | S1PR1 (0.76) | S1PR1TNNC1S1PR3SGPL1S1PR4 | |
| SCHEMBL6527719 | 0.90 | S1PR1 (0.65) | S1PR1TNNC1S1PR3SGPL1S1PR4 | |
| SCHEMBL6508260 | 0.87 | S1PR1 (0.61) | S1PR1TNNC1S1PR3SGPL1S1PR4 | |
| SCHEMBL6531435 | 0.86 | S1PR1 (0.78) | S1PR1TNNC1S1PR3SGPL1S1PR4 | |
| SCHEMBL6507062 | 0.86 | S1PR1 (0.60) | S1PR1TNNC1S1PR3SGPL1S1PR4 | |
| SCHEMBL10980032 | 0.82 | SMN1; SMN2 (0.61) | S1PR1S1PR3GLASMN1; SMN2BACE1 | |
| SCHEMBL10974737 | 0.82 | SMN1; SMN2 (0.61) | S1PR1S1PR3GLASMN1; SMN2BACE1 | |
| SCHEMBL9399173 | 0.81 | SMN1; SMN2 (0.59) | S1PR1GLASMN1; SMN2BACE1 | |
| SCHEMBL10980962 | 0.81 | SMN1; SMN2 (0.59) | S1PR1GLASMN1; SMN2BACE1 | |
| Hydrochloric Acid SCHEMBL6506579 | 0.81 | S1PR1 (0.62) | S1PR1TNNC1S1PR3SGPL1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | claimed |