SCHEMBL65292

SCHEMBL65292

CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.34
MGLL Q99685 2/20 0.34
TUBB4A P04350 1/20 0.32
TUBB P07437 1/20 0.32
TUBA3C P0DPH7 1/20 0.32
TUBA1B P68363 1/20 0.32
TUBA4A P68366 1/20 0.32
TUBB4B P68371 1/20 0.32
TUBB3 Q13509 1/20 0.32
TUBB2A Q13885 1/20 0.32
TUBB8 Q3ZCM7 1/20 0.32
TUBA3E Q6PEY2 1/20 0.32
TUBA1A Q71U36 1/20 0.32
TUBA1C Q9BQE3 1/20 0.32
TUBB6 Q9BUF5 1/20 0.32
TUBB2B Q9BVA1 1/20 0.32
TUBB1 Q9H4B7 1/20 0.32
KRAS P01116 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23088800 1.00 FAAH (0.34) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL29351838 1.00 FAAH (0.34) FAAHMGLLTUBB4ATUBBTUBA3C
Hydrochloric Acid SCHEMBL29369852 0.99 FAAH (0.33) FAAHMGLLTUBB4ATUBBTUBA3C
Hydrochloric Acid SCHEMBL29819885 0.99 FAAH (0.33) FAAHMGLLTUBB4ATUBBTUBA3C
Hydrochloric Acid SCHEMBL20241832 0.99 FAAH (0.33) FAAHMGLLTUBB4ATUBBTUBA3C
Methylamine SCHEMBL28480158 0.98 FAAH (0.33) FAAHMGLLTUBB4ATUBBTUBA3C
Methane SCHEMBL20657745 0.98 FAAH (0.33) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL28376004 0.98 FAAH (0.33) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL29359375 0.95 FAAH (0.36) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL241113 0.95 FAAH (0.36) FAAHMGLLTUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2123 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240262934-A1 STARCH-INDOLE-ACID DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF SHANDONG SHANWEI IMMUNOTECH CO., LTD. (CN) 2024-08-08 US claimed
EP-3842425-B1 NOVEL QUINOLINE DERIVATIVE INHIBITOR TRANSTHERA SCIENCES NANJING INC (CN) 2024-05-22 EP claimed
US-11891602-B2 Method of producing hairpin single-stranded RNA molecules TORAY INDUSTRIES, INC. (JP) 2024-02-06 US claimed
US-11827612-B2 Hydroxamic acid derivative, method for producing same and use thereof INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2023-11-28 US claimed
US-11702444-B2 Method for preparing natural bioactive peptide Tubulysin U SHENZHEN INSTITUTE OF GERIATRICS (CN) 2023-07-18 US claimed
WO-2023105497-A1 SYNTHESIS OF GLP-1 ANALOGUES ANTHEM BIOSCIENCES PVT. LTD. (IN) 2023-06-15 WO claimed
US-20230174479-A1 CYANINE-DERIVED COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF NANJING GENVIVO BIOTECH CO., LTD. (CN) 2023-06-08 US claimed
US-20230099436-A1 METHOD FOR PREPARING NATURAL BIOACTIVE PEPTIDE TUBULYSIN U SHENZHEN INSTITUTE OF GERIATRICS (CN) 2023-03-30 US claimed
EP-4079723-A1 CYANINE DERIVATIVE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Nanjing Genvivo Biotech Co., Ltd. (CN) 2022-10-26 EP claimed
CN-115197090-A Amide derivative of multi-caffeoyl quinic acid, preparation method and application thereof 泰米西斯公司 2022-10-18 CN claimed
CN-113087784-A Somalufide amino-terminal formaldehide and preparation method thereof 齐鲁制药有限公司 2021-07-09 CN claimed
EP-3842425-A1 NOVEL QUINOLINE DERIVATIVE INHIBITOR Nanjing Transthera Biosciences Co., Ltd. (CN) 2021-06-30 EP claimed
US-10894773-B2 Deuterated CFTR potentiators VERTEX PHARMACEUTICALS (EUROPE) LIMITED (GB) 2021-01-19 US claimed
US-20200290971-A1 DEUTERATED CFTR POTENTIATORS VERTEX PHARMACEUTICALS (EUROPE) LIMITED (GB) 2020-09-17 US claimed
CN-111349153-A Preparation method of atrial natriuretic peptide 四川吉晟生物医药有限公司 2020-06-30 CN claimed
CN-107531614-B Preparation method of delogevir 迈兰实验室有限公司 2020-04-10 CN claimed
CN-110964097-A Synthesis of exenatide by solid-phase fragment method 南京华威医药科技集团有限公司 2020-04-07 CN claimed
US-10479766-B2 Deuterated CFTR potentiators Verex Pharmaceuticals (Europe) Limited (GB) 2019-11-19 US claimed
US-20190169129-A1 DEUTERATED CFTR POTENTIATORS VERTEX PHARMACEUTICALS (EUROPE) LIMITED (GB) 2019-06-06 US claimed
US-20180086711-A1 DEUTERATED CFTR POTENTIATORS VERTEX PHARMACEUTICALS (EUROPE) LIMITED (GB) 2018-03-29 US claimed