Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 7/20 | 0.56 |
| ▸ | HTR2A | P28223 | 6/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9120332 | 0.93 | HRH1 (0.62) | HRH1HTR2ASIGMAR1CYP19A1FOLH1 | |
| SCHEMBL9073997 | 0.85 | HRH1 (0.71) | HRH1HTR2ASIGMAR1CYP19A1 | |
| SCHEMBL4811034 | 0.80 | HRH1 (0.56) | HRH1HTR2ASIGMAR1 | |
| SCHEMBL1861354 | 0.78 | RIPK1 (0.52) | HRH1HTR2ASIGMAR1HDAC3HDAC4 | |
| SCHEMBL23581510 | 0.77 | HRH1 (0.56) | HRH1HTR2ASIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL17529779 | 0.77 | HRH1 (0.56) | HRH1HTR2ASIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL8533810 | 0.77 | HRH1 (0.56) | HRH1HTR2ASIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL1204774 | 0.77 | HRH1 (0.83) | HRH1HTR2ASIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL3389109 | 0.77 | HRH1 (0.56) | HRH1HTR2ASIGMAR1CYP19A1TBXAS1 | |
| SCHEMBL2849801 | 0.77 | HRH1 (0.83) | HRH1HTR2ASIGMAR1CYP19A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050101063-A1 | Three-terminal field-controlled molecular devices | TOUR JAMES M (US) | 2005-05-12 | — | — | US | disclosed |