SCHEMBL6529302

SCHEMBL6529302

Cc1c(CC(=O)O)c2cc(F)ccc2n1S(=O)(=O)c1cc(Cl)cc(Cl)c1

nearest known ligand 0.84

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 18/20 0.84
PTGDR Q13258 5/20 0.84
AKR1C3 P42330 2/20 0.57
AKR1C2 P52895 2/20 0.57
CCKAR P32238 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6531234 0.91 PTGDR2 (1.00) PTGDR2PTGDRAKR1C3AKR1C2CCKAR
SCHEMBL6531329 0.87 PTGDR2 (1.00) PTGDR2PTGDRAKR1C3AKR1C2
SCHEMBL1222480 0.85 PTGDR2 (1.00) PTGDR2PTGDRAKR1C3AKR1C2CCKAR
SCHEMBL6527650 0.83 PTGDR2 (0.86) PTGDR2PTGDRAKR1C3AKR1C2CCKAR
SCHEMBL6530349 0.83 PTGDR2 (1.00) PTGDR2PTGDRAKR1C3AKR1C2
SCHEMBL6503751 0.82 PTGDR2 (0.74) PTGDR2PTGDRAKR1C3AKR1C2CCKAR
SCHEMBL6533995 0.81 PTGDR2 (0.73) PTGDR2PTGDRAKR1C3AKR1C2CCKAR
SCHEMBL6527998 0.81 PTGDR2 (0.82) PTGDR2PTGDRAKR1C3AKR1C2CCKAR
SCHEMBL6529157 0.80 PTGDR2 (0.72) PTGDR2PTGDRAKR1C3AKR1C2CCKAR
SCHEMBL6532413 0.80 PTGDR2 (0.81) PTGDR2PTGDRAKR1C3AKR1C2CCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005040112-A1 COMPOUNDS WITH PGD2 ANTAGONIST ACTIVITY OXAGEN LIMITED (GB) 2005-05-06 WO disclosed