Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 18/20 | 0.81 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.81 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.48 |
| ▸ | CCKAR | P32238 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531329 | 0.87 | PTGDR2 (1.00) | PTGDR2PTGDRAKR1C3AKR1C2 | |
| SCHEMBL6527650 | 0.87 | PTGDR2 (0.86) | PTGDR2PTGDRAKR1C3AKR1C2CCKAR | |
| SCHEMBL6529284 | 0.83 | PTGDR2 (0.73) | PTGDR2PTGDRAKR1C3AKR1C2CCKAR | |
| SCHEMBL6529948 | 0.82 | PTGDR2 (0.78) | PTGDR2PTGDRAKR1C3AKR1C2CCKAR | |
| SCHEMBL6503751 | 0.81 | PTGDR2 (0.74) | PTGDR2PTGDRAKR1C3AKR1C2CCKAR | |
| SCHEMBL1222480 | 0.81 | PTGDR2 (1.00) | PTGDR2PTGDRAKR1C3AKR1C2CCKAR | |
| SCHEMBL6529302 | 0.80 | PTGDR2 (0.84) | PTGDR2PTGDRAKR1C3AKR1C2CCKAR | |
| SCHEMBL6531234 | 0.80 | PTGDR2 (1.00) | PTGDR2PTGDRAKR1C3AKR1C2CCKAR | |
| SCHEMBL6529581 | 0.79 | PTGDR2 (0.69) | PTGDR2PTGDRAKR1C3AKR1C2CCKAR | |
| SCHEMBL6530997 | 0.79 | PTGDR2 (0.73) | PTGDR2PTGDRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040112-A1 | COMPOUNDS WITH PGD2 ANTAGONIST ACTIVITY | OXAGEN LIMITED (GB) | 2005-05-06 | — | — | WO | disclosed |