Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9352742 | 0.76 | SLC6A4 (0.43) | SLC6A4MTNR1AHTR1BKDM1A | |
| SCHEMBL6790827 | 0.75 | SLC6A4 (0.48) | SLC6A4KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9482107 | 0.75 | SLC6A4 (0.42) | SLC6A4MTNR1AHTR1BKDM1A | |
| SCHEMBL7094962 | 0.73 | MAPT (0.56) | SLC6A4MTNR1AMTNR1BMAPTF2 | |
| Ammonia Solution, Strong SCHEMBL27509223 | 0.72 | MAPT (0.55) | SLC6A4MTNR1AMTNR1BMAPTF2 | |
| SCHEMBL7010711 | 0.71 | MTNR1A (0.51) | SLC6A4MTNR1AMTNR1BMAPTF2 | |
| SCHEMBL27997503 | 0.70 | F2 (0.64) | SLC6A4MTNR1AMTNR1BMAPTF2 | |
| SCHEMBL2702986 | 0.70 | SLC6A4 (0.67) | SLC6A4MTNR1AMTNR1B | |
| SCHEMBL649532 | 0.70 | ACACB (0.54) | MTNR1A | |
| SCHEMBL649531 | 0.70 | ACACB (0.54) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537096-A2 | DERIVATIVES OF DIOXANE-2-ALKYL CARBAMATES, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004020430-A2 | DERIVATIVES OF DIOXANE-2-ALKYL CARBAMATES, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2004-03-11 | — | — | WO | disclosed |