Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 6/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.41 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5372934 | 0.92 | MRGPRX4 (0.55) | MRGPRX4PTGDR2MAOBSGMS2ALDH1A1 | |
| SCHEMBL5367447 | 0.88 | PTGDR2 (0.60) | PTGDR2MAOBCCR5SLC6A4LMNA | |
| SCHEMBL6530691 | 0.84 | PTGDR2 (0.56) | PTGDR2MAOBCCR5SLC6A4LMNA | |
| SCHEMBL7115963 | 0.79 | MRGPRX4 (0.50) | MRGPRX4MAOBCCR5SGMS2ALDH1A1 | |
| SCHEMBL7123539 | 0.79 | MRGPRX4 (0.58) | MRGPRX4PTGDR2MAOBSGMS2RXRA | |
| Hydrochloric Acid SCHEMBL7528063 | 0.78 | MRGPRX4 (0.57) | MRGPRX4PTGDR2MAOBSGMS2RXRA | |
| SCHEMBL15912886 | 0.77 | ALOX5AP (0.54) | MRGPRX4PTGDR2MAOBCCR5SLC6A4 | |
| SCHEMBL1980141 | 0.77 | MAOB (0.58) | MRGPRX4MAOBCCR5SLC6A4ALDH1A1 | |
| SCHEMBL7116783 | 0.77 | MRGPRX4 (0.56) | MRGPRX4PTGDR2MAOBSGMS2RXRA | |
| SCHEMBL3726426 | 0.74 | PTGER1 (0.54) | MRGPRX4MAOBCCR5SLC6A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005023762-A1 | PYRROLIDINE-2-CARBONITRILE DERIVATIVES AND THEIR USE AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2005-03-17 | — | — | WO | disclosed |