Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | BACE1 | P56817 | 9/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | CTSD | P07339 | 5/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527555 | 0.89 | BACE1 (0.43) | F2BACE1BCHEBACE2 | |
| SCHEMBL6526643 | 0.89 | F2 (0.46) | F2BACE1BCHECTSDBACE2 | |
| SCHEMBL6528687 | 0.87 | BACE1 (0.48) | F2BACE1BCHECTSD | |
| SCHEMBL6526561 | 0.87 | NPC1 (0.42) | BACE1NPC1RAB9A | |
| SCHEMBL7461164 | 0.87 | BACE1 (0.44) | F2BACE1CTSDBACE2 | |
| SCHEMBL6527915 | 0.84 | BACE1 (0.40) | F2BACE1CTSDBACE2 | |
| SCHEMBL5981669 | 0.82 | BACE1 (0.42) | F2BACE1BCHECTSDBACE2 | |
| SCHEMBL7461153 | 0.82 | F2 (0.38) | F2BACE1NPC1RAB9A | |
| SCHEMBL6527345 | 0.81 | F2 (0.44) | F2BACE1BCHECTSDBACE2 | |
| SCHEMBL6527142 | 0.81 | BACE1 (0.43) | F2BACE1BCHECTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3657002-B2 | — | — | 2005-06-08 | — | — | JP | claimed |
| WO-1994004492-A1 | HYDROXYETHYLAMINO SULFONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1994-03-03 | — | — | WO | claimed |