Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.59 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.59 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.59 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530617 | 0.89 | DPP4 (0.69) | DPP4DPP8DPP7FKBP1A | |
| SCHEMBL6529872 | 0.88 | DPP4 (0.71) | DPP4DPP8DPP7 | |
| SCHEMBL6532088 | 0.87 | DPP4 (0.55) | DPP4DPP8DPP7FKBP1A | |
| SCHEMBL6528023 | 0.87 | DPP4 (0.54) | DPP4DPP8DPP7FKBP1A | |
| SCHEMBL6531569 | 0.82 | DPP4 (0.82) | DPP4DPP8DPP7 | |
| SCHEMBL6532895 | 0.82 | DPP4 (0.75) | DPP4DPP8DPP7 | |
| SCHEMBL6529460 | 0.81 | DPP4 (0.68) | DPP4DPP8DPP7FKBP1A | |
| SCHEMBL6531771 | 0.78 | DPP4 (0.81) | DPP4DPP8DPP7 | |
| SCHEMBL6533255 | 0.78 | DPP4 (0.56) | DPP4DPP8DPP7 | |
| SCHEMBL6533252 | 0.78 | DPP4 (0.56) | DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |