Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.65 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5156297 | 1.00 | MAPT (0.65) | MAPTCYP3A4CYP2C19TRPM8CYP2D6 | |
| SCHEMBL1526906 | 0.88 | RAB9A (0.50) | MAPTCYP3A4CYP2C19TRPM8CYP2D6 | |
| Asarinin SCHEMBL30384235 | 0.79 | MAPT (1.00) | MAPTCYP3A4CYP2C19TRPM8CYP2D6 | |
| Asarinin SCHEMBL94518 | 0.79 | MAPT (1.00) | MAPTCYP3A4CYP2C19TRPM8CYP2D6 | |
| Asarinin SCHEMBL30184024 | 0.79 | MAPT (1.00) | MAPTCYP3A4CYP2C19TRPM8CYP2D6 | |
| Sesamin SCHEMBL23045677 | 0.79 | MAPT (1.00) | MAPTCYP3A4CYP2C19TRPM8CYP2D6 | |
| Asarinin SCHEMBL3498030 | 0.79 | MAPT (1.00) | MAPTCYP3A4CYP2C19TRPM8CYP2D6 | |
| Asarinin SCHEMBL6704290 | 0.79 | MAPT (1.00) | MAPTCYP3A4CYP2C19TRPM8CYP2D6 | |
| Asarinin SCHEMBL19313765 | 0.79 | MAPT (1.00) | MAPTCYP3A4CYP2C19TRPM8CYP2D6 | |
| Asarinin SCHEMBL29540276 | 0.79 | MAPT (1.00) | MAPTCYP3A4CYP2C19TRPM8CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003140-A1 | 4-OXO-4,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-01-13 | — | — | WO | disclosed |