Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FPR1 | P21462 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PDE9A | O76083 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528422 | 0.90 | L3MBTL1 (0.60) | L3MBTL1OGFRL1OPRM1OPRK1HSD17B10 | |
| SCHEMBL6532045 | 0.88 | L3MBTL1 (0.58) | L3MBTL1CSNK2A1OGFRL1OPRM1OPRK1 | |
| SCHEMBL6529611 | 0.86 | EGFR (0.43) | EGFROGFRL1OPRM1OPRK1KDM4E | |
| SCHEMBL6530897 | 0.85 | L3MBTL1 (0.60) | L3MBTL1EGFROGFRL1OPRM1OPRK1 | |
| SCHEMBL6530018 | 0.84 | L3MBTL1 (0.55) | L3MBTL1OGFRL1OPRM1OPRK1HSD17B10 | |
| SCHEMBL14383408 | 0.84 | L3MBTL1 (0.49) | L3MBTL1CSNK2A1OGFRL1OPRM1OPRK1 | |
| SCHEMBL14383413 | 0.83 | L3MBTL1 (0.48) | L3MBTL1CSNK2A1EGFROGFRL1OPRM1 | |
| SCHEMBL14383414 | 0.83 | L3MBTL1 (0.48) | L3MBTL1CSNK2A1OGFRL1OPRM1OPRK1 | |
| SCHEMBL14383207 | 0.83 | L3MBTL1 (0.52) | L3MBTL1CSNK2A1OGFRL1OPRM1OPRK1 | |
| SCHEMBL6530892 | 0.82 | L3MBTL1 (0.58) | L3MBTL1CSNK2A1OGFRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019186-A1 | 2-AMINOBENZIMIDAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF HIV/AIDS | BAYER HEALTHCARE AG (DE) | 2005-03-03 | — | — | WO | disclosed |