Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD5 | P21918 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31510878 | 0.84 | HTR2A (0.51) | HTR2AHTR2CNR2E1CHRNA7TAAR1 | |
| SCHEMBL31510880 | 0.84 | HTR2A (0.51) | HTR2AHTR2CNR2E1CHRNA7TAAR1 | |
| SCHEMBL17999481 | 0.81 | F9 (0.39) | BAZ2BACHE | |
| SCHEMBL31684725 | 0.79 | HTR2A (0.46) | HTR2AHTR2CNR2E1CHRNA7TAAR1 | |
| SCHEMBL4652083 | 0.78 | HTR2A (0.45) | HTR2AHTR2CNR2E1CHRNA7TAAR1 | |
| SCHEMBL4651124 | 0.78 | HTR2A (0.45) | HTR2AHTR2CNR2E1CHRNA7TAAR1 | |
| SCHEMBL14029096 | 0.78 | HTR2A (0.45) | HTR2AHTR2CNR2E1CHRNA7TAAR1 | |
| SCHEMBL1114261 | 0.77 | LMNA (0.45) | HTR2AHTR2CNR2E1CHRNA7TAAR1 | |
| SCHEMBL6526481 | 0.77 | LMNA (0.45) | HTR2AHTR2CNR2E1CHRNA7TAAR1 | |
| SCHEMBL4280139 | 0.75 | HTR2A (0.49) | HTR2AHTR2CNR2E1CHRNA7TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033099-A2 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS; PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS THEREOF | GLENMARK PHARMACEUTICALS LTD. (US) | 2005-04-14 | — | — | WO | disclosed |