Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.70 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.70 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.70 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529685 | 0.82 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL6531062 | 0.82 | DPP4 (0.53) | DPP4DPP8DPP7 | |
| SCHEMBL6530262 | 0.80 | DPP4 (0.45) | DPP4DPP8DPP7 | |
| SCHEMBL6507359 | 0.75 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL6531774 | 0.74 | DPP4 (0.84) | DPP4DPP8DPP7 | |
| SCHEMBL6532892 | 0.72 | DPP4 (0.53) | DPP4DPP8DPP7HDAC4DPP9 | |
| SCHEMBL6530998 | 0.72 | DPP4 (0.76) | DPP4DPP8DPP7 | |
| SCHEMBL6529428 | 0.71 | DPP4 (0.66) | DPP4DPP8DPP7HDAC4DPP9 | |
| SCHEMBL6529292 | 0.71 | DPP4 (0.66) | DPP4DPP8DPP7HDAC4DPP9 | |
| SCHEMBL6530653 | 0.70 | DPP4 (1.00) | DPP4DPP8DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |