Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.66 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.66 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529292 | 1.00 | DPP4 (0.66) | DPP4DPP8DPP7HDAC4HDAC6 | |
| SCHEMBL6529447 | 0.88 | DPP4 (0.51) | DPP4DPP8DPP7HSD11B1PIK3CA | |
| SCHEMBL6531352 | 0.81 | DPP4 (0.45) | DPP4DPP8DPP7 | |
| SCHEMBL6507359 | 0.80 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL6532393 | 0.80 | DPP4 (0.61) | DPP4DPP8DPP7HSD11B1CYP1A2 | |
| SCHEMBL6533019 | 0.80 | DPP4 (0.61) | DPP4DPP8DPP7POLB | |
| SCHEMBL6530249 | 0.80 | DPP4 (0.61) | DPP4DPP8DPP7HSD11B1CYP1A2 | |
| SCHEMBL6529685 | 0.77 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL6530998 | 0.74 | DPP4 (0.76) | DPP4DPP8DPP7 | |
| SCHEMBL6531069 | 0.74 | DPP4 (0.70) | DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |