Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.69 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.69 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.69 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6519353 | 0.92 | DPP4 (0.58) | DPP4DPP8DPP7ACKR3TSHR | |
| SCHEMBL6530003 | 0.91 | DPP4 (0.58) | DPP4DPP8DPP7ACKR3 | |
| SCHEMBL6530979 | 0.88 | DPP4 (0.55) | DPP4DPP8DPP7ACKR3 | |
| SCHEMBL6528758 | 0.82 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL6530653 | 0.81 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL6530636 | 0.81 | DPP4 (0.74) | DPP4DPP8DPP7 | |
| SCHEMBL6528164 | 0.81 | DPP4 (0.78) | DPP4DPP8DPP7 | |
| SCHEMBL6530464 | 0.80 | DPP4 (0.77) | DPP4DPP8DPP7 | |
| SCHEMBL6528825 | 0.80 | USP30 (0.47) | DPP4DPP8DPP7 | |
| SCHEMBL6532358 | 0.78 | DPP4 (0.74) | DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |