Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.55 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530003 | 0.94 | DPP4 (0.58) | DPP4DPP7DPP8ACKR3SPHK2 | |
| SCHEMBL6529796 | 0.88 | DPP4 (0.69) | DPP4DPP7DPP8ACKR3 | |
| SCHEMBL6519353 | 0.87 | DPP4 (0.58) | DPP4DPP7DPP8ACKR3SPHK2 | |
| SCHEMBL6530976 | 0.87 | ACKR3 (0.39) | DPP4DPP7DPP8ACKR3SPHK2 | |
| SCHEMBL6529876 | 0.84 | DPP4 (0.75) | DPP4DPP7DPP8 | |
| SCHEMBL6532895 | 0.83 | DPP4 (0.75) | DPP4DPP7DPP8 | |
| SCHEMBL6527703 | 0.83 | DPP4 (0.59) | DPP4DPP7DPP8 | |
| SCHEMBL6529453 | 0.82 | DPP4 (0.58) | DPP4DPP7DPP8 | |
| SCHEMBL6530130 | 0.78 | DPP4 (0.54) | DPP4DPP7DPP8 | |
| SCHEMBL6531771 | 0.78 | DPP4 (0.81) | DPP4DPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |