Lithium Ion

SCHEMBL6529894

CC(C)(C)[O-].CON=C1N(C)c2ccc(N3C[C@@H](CNC(=O)OC(C)(C)C)OC3=O)cc2C1(F)F.[Li+]

nearest known ligand 0.43

Known targets — ChEMBL curated mechanism

The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	F10	P00742	12/20	0.43

▸	MAOB	P27338	6/20	0.43

▸	MAOA	P21397	5/20	0.43

▸	LMNA	P02545	1/20	0.43

▸	PTGS1	P23219	1/20	0.43

▸	CALML3	P27482	1/20	0.43

▸	SDHA	P31040	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6532044	0.97	MAOB (0.45)	F10MAOBMAOALMNAPTGS1
SCHEMBL6532041	0.97	MAOB (0.45)	F10MAOBMAOALMNAPTGS1
Lithium Ion SCHEMBL6531166	0.92	MAOA (0.50)	F10MAOBMAOALMNAPTGS1
SCHEMBL6529220	0.90	MAOA (0.46)	F10MAOBMAOALMNAPTGS1
SCHEMBL6529223	0.90	MAOA (0.46)	F10MAOBMAOALMNAPTGS1
SCHEMBL6530878	0.87	MAOA (0.54)	F10MAOBMAOALMNAPTGS1
SCHEMBL6528613	0.87	MAOA (0.54)	F10MAOBMAOALMNAPTGS1
SCHEMBL6528609	0.87	MAOA (0.54)	F10MAOBMAOALMNAPTGS1
SCHEMBL6533404	0.85	MAOB (0.45)	F10MAOBMAOALMNAPTGS1
SCHEMBL6533407	0.85	MAOB (0.45)	F10MAOBMAOALMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2005082900-A2	OXAZOLIDINONE AMIDOXIMES AS ANTIBACTERIAL AGENTS	PHARMACIA & UPJOHN COMPANY LLC (US)	2005-09-09	—	—	WO	disclosed