Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12092154 | 0.87 | MEN1 (0.40) | TSHRALDH1A1GAASMN1; SMN2PKM | |
| SCHEMBL12080288 | 0.86 | MEN1 (0.42) | TSHRALDH1A1GAASMN1; SMN2PKM | |
| SCHEMBL6526014 | 0.83 | NPSR1 (0.42) | TSHRALDH1A1GAASMN1; SMN2PKM | |
| SCHEMBL5049683 | 0.83 | ALDH1A1 (0.48) | TSHRALDH1A1GAASMN1; SMN2PKM | |
| Hydrochloric Acid SCHEMBL25357568 | 0.82 | NPSR1 (0.41) | TSHRALDH1A1GAASMN1; SMN2PKM | |
| Hydrochloric Acid SCHEMBL12080073 | 0.82 | NPSR1 (0.41) | TSHRALDH1A1GAASMN1; SMN2PKM | |
| SCHEMBL12092163 | 0.79 | TSHR (0.43) | TSHRALDH1A1GAASMN1; SMN2PKM | |
| SCHEMBL5793627 | 0.79 | TSHR (0.41) | TSHRALDH1A1GAASMN1; SMN2PKM | |
| SCHEMBL1341702 | 0.78 | TSHR (0.43) | TSHRALDH1A1GAASMN1; SMN2MEN1 | |
| SCHEMBL22743444 | 0.77 | HRH2 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6894052-B1 | Serotonergic receptor antagonist | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2005-05-17 | — | — | US | disclosed |
| EP-1000046-B1 | PIPERAZINE DERIVATIVES ACTIVE ON THE LOWER URINARY TRACT | RECORDATI CHEM PHARM (CH) | 2003-11-26 | — | — | EP | disclosed |
| EP-1000046-A1 | PIPERAZINE DERIVATIVES ACTIVE ON THE LOWER URINARY TRACT | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999006383-A1 | PIPERAZINE DERIVATIVES ACTIVE ON THE LOWER URINARY TRACT | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1999-02-11 | — | — | WO | disclosed |