Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | UNG | P13051 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.36 |
| ▸ | ABAT | P80404 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzaldehyde SCHEMBL6862921 | 0.93 | ALDH1A1 (0.61) | ALDH1A1CYP2A6LMNATRPA1ALOX5 | |
| SCHEMBL92340 | 0.83 | CYP2A6 (0.46) | ALDH1A1CYP2A6HDAC8HSD17B10ALDH5A1 | |
| Phenylacetylene SCHEMBL28137099 | 0.81 | HDAC8 (0.44) | ALDH1A1CYP2A6APPCYP2C9HDAC8 | |
| Phenylacetylene SCHEMBL27475394 | 0.81 | APP (0.39) | ALDH1A1CYP2A6APPCYP2C9HDAC8 | |
| Phenylacetylene SCHEMBL27256635 | 0.81 | PTPN1 (0.39) | ALDH1A1CYP2A6MAPK1APPCYP2C9 | |
| SCHEMBL577853 | 0.80 | ALDH1A1 (0.48) | ALDH1A1CYP2A6UNGFFAR1 | |
| SCHEMBL29569326 | 0.80 | ALDH1A1 (0.48) | ALDH1A1CYP2A6UNGFFAR1 | |
| Benzaldehyde SCHEMBL28968614 | 0.80 | ALDH1A1 (0.88) | ALDH1A1CYP2A6LMNATRPA1ALOX5 | |
| Benzaldehyde SCHEMBL28138348 | 0.80 | ALDH1A1 (0.88) | ALDH1A1CYP2A6LMNATRPA1ALOX5 | |
| Phenylacetylene SCHEMBL4297769 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115504953-A | Preparation method of 3-isocoumarin chromone compound | 昆明理工大学 | 2022-12-23 | — | — | CN | disclosed |
| CN-114751806-A | Diaryl acetylene compound and preparation method thereof | 上海泰坦科技股份有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-107445835-B | Synthesis method of 1, 2-dihydro cyclobuteno [ a ] naphthalene derivative and precursor thereof | 江苏师范大学 | 2020-09-22 | — | — | CN | disclosed |
| US-8680150-B2 | Small molecule hematopoietic growth factor mimetic compounds that activate hematopoietic growth factor receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-20110003851-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS THAT ACTIVATE HEMATOPOIETIC GROWTH FACTOR RECEPTORS | LIGAND PHARMACEUTICALS, INC. (US) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003851-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS THAT ACTIVATE HEMATOPOIETIC GROWTH FACTOR RECEPTORS | MPL, CSF3R, CSF1R | ALDH1A1 3164/4885CYP2A6 4472/4885LMNA 4304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.