Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.64 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.52 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | UNG | P13051 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzaldehyde SCHEMBL28675359 | 0.93 | ALDH1A1 (0.67) | ALDH1A1CYP2A6TRIM24TRIM33CA12 | |
| SCHEMBL28460866 | 0.86 | TRIM24 (0.67) | ALDH1A1CYP2A6TRIM24TRIM33CA12 | |
| SCHEMBL29936157 | 0.86 | ALDH1A1 (0.56) | ALDH1A1CYP2A6TRIM24TRIM33CA12 | |
| SCHEMBL13617691 | 0.86 | ALDH1A1 (0.56) | ALDH1A1CYP2A6TRIM24TRIM33CA12 | |
| SCHEMBL29936396 | 0.86 | ALDH1A1 (0.56) | ALDH1A1CYP2A6TRIM24TRIM33CA12 | |
| Benzaldehyde SCHEMBL28138348 | 0.85 | ALDH1A1 (0.88) | ALDH1A1CYP2A6UNGMAOAMAOB | |
| Benzaldehyde SCHEMBL28968614 | 0.85 | ALDH1A1 (0.88) | ALDH1A1CYP2A6UNGMAOAMAOB | |
| SCHEMBL97618 | 0.84 | TRIM24 (0.69) | ALDH1A1CYP2A6TRIM24TRIM33CA12 | |
| SCHEMBL29414645 | 0.84 | TRIM24 (0.69) | ALDH1A1CYP2A6TRIM24TRIM33CA12 | |
| Biphenyl SCHEMBL2390667 | 0.83 | ALDH1A1 (0.82) | ALDH1A1CYP2A6TRIM24TRIM33CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680150-B2 | Small molecule hematopoietic growth factor mimetic compounds that activate hematopoietic growth factor receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-20110003851-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS THAT ACTIVATE HEMATOPOIETIC GROWTH FACTOR RECEPTORS | LIGAND PHARMACEUTICALS, INC. (US) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003851-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS THAT ACTIVATE HEMATOPOIETIC GROWTH FACTOR RECEPTORS | MPL, CSF3R, CSF1R | ALDH1A1 3164/4885CYP2A6 4472/4885TRIM24 484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.