Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.47 |
| ▸ | PPARA | Q07869 | 17/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529516 | 0.93 | PPARG (0.41) | PPARGPPARAPPARDALDH1A1TP53 | |
| SCHEMBL6529515 | 0.93 | PPARG (0.41) | PPARGPPARAPPARDALDH1A1TP53 | |
| SCHEMBL6527380 | 0.91 | PPARG (0.49) | PPARGPPARA | |
| SCHEMBL6528958 | 0.81 | PPARG (0.32) | PPARGPPARAFFAR1 | |
| SCHEMBL6504733 | 0.81 | PPARG (0.51) | PPARGPPARA | |
| SCHEMBL6527921 | 0.80 | PPARG (0.30) | PPARGPPARA | |
| SCHEMBL6527918 | 0.80 | PPARG (0.30) | PPARGPPARA | |
| SCHEMBL6527748 | 0.76 | PPARG (0.44) | PPARGPPARA | |
| SCHEMBL6530450 | 0.72 | PPARG (0.55) | PPARGPPARAPPARDTP53FFAR1 | |
| SCHEMBL6530453 | 0.66 | FFAR1 (0.62) | PPARGPPARATP53FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | claimed |
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |