Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530560 | 1.00 | DPP4 (0.38) | DPP4DPP8DPP7ELANE | |
| SCHEMBL4316747 | 0.79 | ELANE (0.45) | DPP4DPP8DPP7ELANE | |
| SCHEMBL4316755 | 0.79 | ELANE (0.45) | DPP4DPP8DPP7ELANE | |
| SCHEMBL4316752 | 0.79 | ELANE (0.45) | DPP4DPP8DPP7ELANE | |
| SCHEMBL6532370 | 0.68 | DPP4 (0.49) | DPP4DPP8DPP7ELANE | |
| SCHEMBL12734314 | 0.66 | DPP4 (0.37) | DPP4DPP8DPP7ELANE | |
| SCHEMBL8840142 | 0.66 | PTPN1 (0.39) | DPP4DPP8DPP7ELANE | |
| SCHEMBL24928349 | 0.65 | DPP4 (0.58) | DPP4DPP8DPP7ELANE | |
| SCHEMBL2678471 | 0.65 | DPP4 (0.36) | DPP4DPP8DPP7ELANE | |
| SCHEMBL11122946 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |