Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532324 | 0.85 | DPP4 (0.65) | DPP4DPP8DPP7PREPKDM4E | |
| SCHEMBL6527433 | 0.82 | DPP4 (0.56) | DPP4DPP8DPP7ELANE | |
| SCHEMBL6530229 | 0.81 | DPP4 (0.69) | DPP4DPP8DPP7 | |
| SCHEMBL6528004 | 0.81 | DPP4 (0.69) | DPP4DPP8DPP7 | |
| SCHEMBL6530558 | 0.68 | DPP4 (0.38) | DPP4DPP8DPP7ELANE | |
| SCHEMBL6530560 | 0.68 | DPP4 (0.38) | DPP4DPP8DPP7ELANE | |
| SCHEMBL6531558 | 0.67 | DPP4 (0.67) | DPP4DPP8DPP7 | |
| SCHEMBL6529836 | 0.66 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL6530574 | 0.66 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL6531965 | 0.66 | DPP4 (0.82) | DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |