Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 1.00 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 1.00 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 1.00 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529836 | 0.82 | DPP4 (1.00) | DPP4DPP7DPP8EPHX2FAP | |
| SCHEMBL6530574 | 0.82 | DPP4 (1.00) | DPP4DPP7DPP8EPHX2FAP | |
| SCHEMBL6530583 | 0.80 | DPP4 (0.67) | DPP4DPP7DPP8EPHX2FAP | |
| SCHEMBL6529840 | 0.78 | DPP4 (0.68) | DPP4DPP7DPP8EPHX2FAP | |
| SCHEMBL6509890 | 0.74 | DPP4 (1.00) | DPP4DPP7DPP8FAP | |
| SCHEMBL6511786 | 0.74 | DPP4 (0.83) | DPP4DPP7DPP8EPHX2FAP | |
| SCHEMBL6529329 | 0.71 | DPP4 (0.63) | DPP4DPP7DPP8EPHX2FAP | |
| SCHEMBL6530052 | 0.71 | DPP4 (0.79) | DPP4DPP7DPP8FAP | |
| SCHEMBL6530580 | 0.62 | DPP4 (0.82) | DPP4DPP7DPP8 | |
| SCHEMBL6529279 | 0.62 | DPP4 (0.82) | DPP4DPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |