Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 13/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 12/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 12/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530585 | 1.00 | ITGAL (0.44) | ITGALITGB2ICAM1DRD4KMT2A | |
| SCHEMBL6477737 | 0.94 | ITGAL (0.43) | ITGALITGB2ICAM1DRD4 | |
| SCHEMBL6478538 | 0.88 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL4848413 | 0.88 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL6479285 | 0.88 | ITGAL (0.41) | ITGALITGB2ICAM1 | |
| SCHEMBL4849098 | 0.81 | ITGAL (0.48) | ITGALITGB2ICAM1KMT2AMEN1 | |
| SCHEMBL14254718 | 0.81 | ITGAL (0.48) | ITGALITGB2ICAM1KMT2AMEN1 | |
| SCHEMBL4849061 | 0.81 | ITGAL (0.52) | ITGALITGB2ICAM1 | |
| SCHEMBL4840120 | 0.81 | ITGAL (0.52) | ITGALITGB2ICAM1 | |
| SCHEMBL4847894 | 0.81 | ITGAL (0.52) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897225-B1 | Inhibitors of αLβ2 mediated cell adhesion | TANABE SEIYAKU CO., LTD. (JP) | 2005-05-24 | — | — | US | disclosed |