Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PEPD | P12955 | 1/20 | 0.30 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531352 | 0.82 | DPP4 (0.45) | DPP4DPP8DPP7EP300 | |
| SCHEMBL6530127 | 0.81 | DPP4 (0.56) | DPP4DPP8DPP7ALDH1A1 | |
| SCHEMBL6530249 | 0.80 | DPP4 (0.61) | DPP4DPP8DPP7ALDH1A1PEPD | |
| SCHEMBL6532393 | 0.80 | DPP4 (0.61) | DPP4DPP8DPP7ALDH1A1PEPD | |
| SCHEMBL6533469 | 0.78 | HSD17B10 (0.44) | DPP4DPP8DPP7ALDH1A1TSHR | |
| SCHEMBL6532914 | 0.75 | DPP4 (0.42) | DPP4DPP8DPP7ALDH1A1 | |
| SCHEMBL18591298 | 0.74 | PEPD (0.48) | DPP4DPP8DPP7ALDH1A1PEPD | |
| SCHEMBL476146 | 0.74 | PEPD (0.48) | DPP4DPP8DPP7ALDH1A1PEPD | |
| SCHEMBL2995724 | 0.74 | PEPD (0.48) | DPP4DPP8DPP7ALDH1A1PEPD | |
| SCHEMBL3643891 | 0.74 | PEPD (0.48) | DPP4DPP8DPP7ALDH1A1PEPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |