Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.61 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.61 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.54 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532393 | 1.00 | DPP4 (0.61) | DPP4DPP8DPP7ELANEHSD11B1 | |
| SCHEMBL6530127 | 0.87 | DPP4 (0.56) | DPP4DPP8DPP7HSD11B1ALDH1A1 | |
| SCHEMBL6532914 | 0.81 | DPP4 (0.42) | DPP4DPP8DPP7ALDH1A1PTPN1 | |
| SCHEMBL6530734 | 0.80 | DPP4 (0.44) | DPP4DPP8DPP7ALDH1A1PEPD | |
| SCHEMBL6529428 | 0.80 | DPP4 (0.66) | DPP4DPP8DPP7HSD11B1CYP1A2 | |
| SCHEMBL6529292 | 0.80 | DPP4 (0.66) | DPP4DPP8DPP7HSD11B1CYP1A2 | |
| SCHEMBL6532577 | 0.80 | DPP4 (0.68) | DPP4DPP8DPP7ELANEPEPD | |
| SCHEMBL6532173 | 0.79 | DPP4 (0.83) | DPP4DPP8DPP7 | |
| SCHEMBL6530105 | 0.79 | DPP4 (0.60) | DPP4DPP8DPP7ALDH1A1UCHL1 | |
| SCHEMBL6530405 | 0.79 | DPP4 (0.60) | DPP4DPP8DPP7ALDH1A1UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |