Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366689 | 1.00 | DGAT1 (0.43) | DGAT1CHRM2CHRM1CHRM3MMP2 | |
| SCHEMBL2246619 | 1.00 | DGAT1 (0.43) | DGAT1CHRM2CHRM1CHRM3MMP2 | |
| SCHEMBL6360021 | 0.87 | DGAT1 (0.43) | DGAT1 | |
| SCHEMBL1372061 | 0.87 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL2240973 | 0.83 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL30984403 | 0.78 | DGAT1 (0.36) | DGAT1CHRM2CHRM1CHRM3 | |
| SCHEMBL20775447 | 0.78 | DGAT1 (0.36) | DGAT1CHRM2CHRM1CHRM3 | |
| SCHEMBL21122979 | 0.75 | CHRM2 (0.41) | DGAT1CHRM2CHRM1CHRM3MMP2 | |
| SCHEMBL15721883 | 0.75 | CHRM2 (0.41) | DGAT1CHRM2CHRM1CHRM3MMP2 | |
| SCHEMBL15722038 | 0.75 | CHRM2 (0.41) | DGAT1CHRM2CHRM1CHRM3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100334-A1 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS | PFIZER PRODUCTS INC. (US) | 2005-10-27 | — | — | WO | disclosed |