Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 3/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531094 | 0.90 | MAPT (0.36) | MAPTALDH1A1GAAKDM4ELMNA | |
| SCHEMBL4000451 | 0.78 | MAPT (0.42) | MAPTGAAKDM4ELMNASMN1; SMN2 | |
| SCHEMBL4002178 | 0.78 | ALDH1A1 (0.45) | MAPTALDH1A1GAAKDM4ELMNA | |
| SCHEMBL4986026 | 0.74 | MAPT (0.42) | MAPTALDH1A1GAAKDM4ELMNA | |
| SCHEMBL4984788 | 0.74 | MAPT (0.42) | MAPTALDH1A1GAAKDM4ELMNA | |
| SCHEMBL4006276 | 0.74 | MAPT (0.42) | MAPTALDH1A1GAAKDM4ELMNA | |
| SCHEMBL4006040 | 0.73 | ALDH1A1 (0.43) | MAPTALDH1A1GAAKDM4ELMNA | |
| SCHEMBL4000992 | 0.72 | ALDH1A1 (0.44) | MAPTALDH1A1GAAKDM4ELMNA | |
| SCHEMBL4982412 | 0.72 | ALDH1A1 (0.44) | MAPTALDH1A1GAAKDM4ELMNA | |
| SCHEMBL4985441 | 0.72 | ALDH1A1 (0.44) | MAPTALDH1A1GAAKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019191-A2 | 1, 1-DIOXIDO-4H-1,2,4-BENZOTHIADIAZINE DERIVATE UND VERWANDTE VERBINDUNGEN ALS INHIBITOREN DER HCV POLYMERASE ZUR BEHANDLUNG VON HEPATITIS C | ABBOTT LABORATORIES (US) | 2005-03-03 | — | — | WO | disclosed |