⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763504 | 0.85 | — | — | |
| SCHEMBL87843 | 0.78 | — | — | |
| SCHEMBL2136218 | 0.78 | TSHR (0.42) | — | |
| SCHEMBL2004794 | 0.78 | LMNA (0.55) | — | |
| SCHEMBL6299790 | 0.78 | LMNA (0.55) | — | |
| SCHEMBL1454585 | 0.78 | — | — | |
| SCHEMBL24718244 | 0.77 | — | — | |
| SCHEMBL19371184 | 0.76 | — | — | |
| Ethylene SCHEMBL21634076 | 0.76 | TSHR (0.40) | — | |
| SCHEMBL8960577 | 0.76 | LMNA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101932590-A | 2 ', 4' -substituted nucleosides as antiviral agents | PHARMASSET INC | 2010-12-29 | — | — | CN | claimed |
| CN-85107643-A | The preparation method of the dibenzyl ether compound that replaces and as the purposes of agricultural chemicals | — | 1986-08-20 | — | — | CN | claimed |
| EP-0136451-A2 | Arylmethyl-ether derivatives, pesticides containing these compounds and process for their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-04-10 | — | — | EP | claimed |
| CN-101932590-B | 2 ', 4' -substituted nucleosides as antiviral agents | GILEAD PHARMASSET LLC | 2015-04-15 | — | — | CN | disclosed |
| CN-101932590-A | 2 ', 4' -substituted nucleosides as antiviral agents | PHARMASSET INC | 2010-12-29 | — | — | CN | disclosed |
| EP-1534670-A1 | ENZYME ACTIVATED SELF-IMMOLATIVE N-SUBSTITUTED NITROGEN MUSTARD PRODRUGS | Cancer Research Technology Limited (GB) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004020400-A1 | ENZYME ACTIVATED SELF-IMMOLATIVE N-SUBSTITUTED NITROGEN MUSTARD PRODRUGS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2004-03-11 | — | — | WO | disclosed |
| CN-85107643-A | The preparation method of the dibenzyl ether compound that replaces and as the purposes of agricultural chemicals | — | 1986-08-20 | — | — | CN | disclosed |