Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531265 | 1.00 | CXCR2 (0.42) | CXCR2RELAAHRMAPTKDM4E | |
| SCHEMBL1480448 | 0.90 | RELA (0.46) | CXCR2RELAAHRMAPTKDM4E | |
| SCHEMBL1480451 | 0.90 | RELA (0.46) | CXCR2RELAAHRMAPTKDM4E | |
| SCHEMBL1480745 | 0.90 | CXCR2 (0.49) | CXCR2MAPTIDO1CA12CA1 | |
| SCHEMBL1481070 | 0.87 | MAPT (0.44) | CXCR2RELAAHRMAPTKDM4E | |
| SCHEMBL1481066 | 0.87 | MAPT (0.44) | CXCR2RELAAHRMAPTKDM4E | |
| SCHEMBL1481308 | 0.84 | RELA (0.41) | CXCR2RELAAHRMAPTKDM4E | |
| SCHEMBL1481310 | 0.84 | RELA (0.41) | CXCR2RELAAHRMAPTKDM4E | |
| SCHEMBL1483642 | 0.84 | RELA (0.41) | CXCR2RELAAHRMAPTKDM4E | |
| SCHEMBL1676226 | 0.84 | CXCR2 (0.47) | CXCR2MAPTIDO1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071447-A9 | SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS | TRANSTECH PHARMA INC (US) | 2005-10-13 | — | — | WO | disclosed |