Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531275 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2TSHRPTGDR2HSD17B10ALDH1A1 | |
| SCHEMBL5848241 | 0.91 | SMN1; SMN2 (0.56) | SMN1; SMN2TSHRPTGDR2ALDH1A1HTT | |
| SCHEMBL5848245 | 0.91 | SMN1; SMN2 (0.56) | SMN1; SMN2TSHRPTGDR2ALDH1A1HTT | |
| SCHEMBL5848238 | 0.91 | SMN1; SMN2 (0.56) | SMN1; SMN2TSHRPTGDR2ALDH1A1HTT | |
| SCHEMBL5846752 | 0.84 | PTGDR2 (0.38) | SMN1; SMN2TSHRPTGDR2 | |
| SCHEMBL6527466 | 0.84 | PTGDR2 (0.38) | SMN1; SMN2TSHRPTGDR2 | |
| SCHEMBL5848110 | 0.84 | STING1 (0.42) | SMN1; SMN2PTGDR2ALDH1A1KMT2APKM | |
| SCHEMBL5848117 | 0.84 | STING1 (0.42) | SMN1; SMN2PTGDR2ALDH1A1KMT2APKM | |
| SCHEMBL5848113 | 0.84 | STING1 (0.42) | SMN1; SMN2PTGDR2ALDH1A1KMT2APKM | |
| Hydrochloric Acid SCHEMBL5846749 | 0.83 | PTGDR2 (0.37) | SMN1; SMN2TSHRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005023799-A1 | FUSED BICYCLIC CARBOXAMIDE DERIVATIVES AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2005-03-17 | — | — | WO | disclosed |