Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5846752 | 1.00 | PTGDR2 (0.38) | PTGDR2ENPP2LOXL2POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5846745 | 0.99 | PTGDR2 (0.37) | PTGDR2ENPP2LOXL2POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5846749 | 0.99 | PTGDR2 (0.37) | PTGDR2ENPP2LOXL2POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6527463 | 0.99 | PTGDR2 (0.37) | PTGDR2ENPP2LOXL2POLBSMN1; SMN2 | |
| SCHEMBL6531275 | 0.84 | SMN1; SMN2 (0.56) | PTGDR2SMN1; SMN2TSHR | |
| SCHEMBL6531271 | 0.84 | SMN1; SMN2 (0.56) | PTGDR2SMN1; SMN2TSHR | |
| SCHEMBL5848110 | 0.82 | STING1 (0.42) | PTGDR2POLBSMN1; SMN2 | |
| SCHEMBL5848117 | 0.82 | STING1 (0.42) | PTGDR2POLBSMN1; SMN2 | |
| SCHEMBL5848113 | 0.82 | STING1 (0.42) | PTGDR2POLBSMN1; SMN2 | |
| SCHEMBL23705293 | 0.80 | ADRA2A (0.42) | PTGDR2SMN1; SMN2NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005023799-A1 | FUSED BICYCLIC CARBOXAMIDE DERIVATIVES AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2005-03-17 | — | — | WO | disclosed |