Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3287779 | 0.98 | KDM4E (0.49) | KDM4EMYCSIGMAR1HDAC3HDAC1 | |
| SCHEMBL6531478 | 0.86 | KDM4E (0.44) | KDM4ESIGMAR1HDAC3HDAC1HDAC10 | |
| SCHEMBL2281138 | 0.86 | HDAC6 (0.56) | KDM4ESIGMAR1HDAC3HDAC1HDAC10 | |
| Hydrochloric Acid SCHEMBL1026159 | 0.85 | HDAC6 (0.55) | KDM4ESIGMAR1HDAC3HDAC1HDAC10 | |
| SCHEMBL2281130 | 0.81 | HDAC6 (0.60) | SIGMAR1HDAC3HDAC1HDAC10HDAC11 | |
| Hydrochloric Acid SCHEMBL1027994 | 0.81 | HDAC6 (0.59) | SIGMAR1HDAC3HDAC1HDAC10HDAC11 | |
| SCHEMBL3284599 | 0.78 | KMT2A (0.51) | KDM4EMYCKMT2AHPGDMEN1 | |
| SCHEMBL1082426 | 0.78 | KDM4E (0.40) | KDM4ESIGMAR1SMN1; SMN2KDM1AHDAC6 | |
| SCHEMBL3284900 | 0.78 | ACE (0.42) | KDM4ESIGMAR1KDM1AALDH1A1 | |
| SCHEMBL1026202 | 0.76 | NOTUM (0.61) | MYCKMT2ASMN1; SMN2MEN1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005108367-A1 | COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | ENVIVO PHARMACEUTICALS, INC. (US) | 2005-11-17 | — | — | WO | claimed |