Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3280325 | 0.89 | HDAC6 (0.52) | KMT2ANPC1RAB9AABCB1ABCC1 | |
| SCHEMBL3282233 | 0.84 | MYC (0.58) | KMT2APRMT5WDR77MYCMEN1 | |
| SCHEMBL3284716 | 0.80 | MAPT (0.54) | KMT2ANPC1RAB9APRMT5WDR77 | |
| SCHEMBL29374171 | 0.80 | PRMT5 (0.57) | KMT2APRMT5WDR77MYCMEN1 | |
| SCHEMBL3286990 | 0.80 | NPC1 (0.52) | KMT2ANPC1RAB9AABCB1ABCC1 | |
| Hydroxyamine SCHEMBL6531474 | 0.78 | KDM4E (0.47) | KMT2ANPC1MYCMEN1NLRP3 | |
| SCHEMBL3287779 | 0.78 | KDM4E (0.49) | KMT2ANPC1MYCMEN1NLRP3 | |
| SCHEMBL3280327 | 0.78 | RXRA (0.41) | KMT2AHRH3RXRARXRBRXRG | |
| SCHEMBL28242857 | 0.76 | PRMT5 (0.52) | KMT2ANPC1PRMT5WDR77MYC | |
| SCHEMBL3287775 | 0.76 | MYC (0.57) | KMT2APRMT5WDR77MYCHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705017-B2 | Compounds for treatment of neurodegenerative diseases | EN VIVO PHARMACEUTICALS, INC. (US) | 2010-04-27 | — | — | US | disclosed |