Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.45 |
| ▸ | PPARA | Q07869 | 9/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532464 | 0.92 | PPARA (0.54) | PPARGPPARAPPARD | |
| SCHEMBL6528529 | 0.84 | PPARG (0.47) | PPARGPPARAPPARD | |
| SCHEMBL6529670 | 0.83 | PPARG (0.48) | PPARGPPARATSHRKMT2A | |
| SCHEMBL14265752 | 0.83 | PPARG (0.58) | PPARGPPARAMAPTLMNARXFP1 | |
| SCHEMBL5107137 | 0.83 | PPARG (0.58) | PPARGPPARAMAPTLMNARXFP1 | |
| SCHEMBL1858011 | 0.80 | PPARG (0.45) | PPARGPPARATSHRKMT2AMAPT | |
| SCHEMBL6528743 | 0.79 | PPARG (0.44) | PPARGPPARA | |
| SCHEMBL1858905 | 0.79 | PPARG (0.45) | PPARGPPARATSHRKMT2AMAPT | |
| SCHEMBL5100409 | 0.77 | PPARG (0.54) | PPARGPPARAMAPTLMNARXFP1 | |
| SCHEMBL14286115 | 0.77 | PPARG (0.49) | PPARGPPARAMAPTLMNARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100318-A1 | ALKANOIC ACIDS AND THEIR ESTERS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (US) | 2005-10-27 | — | — | WO | disclosed |
| WO-2005051380-A1 | SUBSTITUTED UREA-OCTAHYDROINDOLS AS ANTAGONISTS OF MELANIN CONCENTRATING HORMONE RECEPTOR 1 (MCH1R) | BIOVITRUM AB (SE) | 2005-06-09 | — | — | WO | disclosed |