⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24425411 | 0.94 | — | — | |
| SCHEMBL1470748 | 0.84 | — | — | |
| SCHEMBL771880 | 0.80 | — | — | |
| SCHEMBL24425403 | 0.80 | — | — | |
| SCHEMBL776518 | 0.73 | — | — | |
| SCHEMBL11981484 | 0.72 | — | — | |
| SCHEMBL16943610 | 0.72 | — | — | |
| SCHEMBL602262 | 0.72 | — | — | |
| SCHEMBL9491253 | 0.72 | — | — | |
| SCHEMBL1897712 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 449 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004780-A | Method for synthesizing polysubstituted pyrrole compound by taking difluoro cyclopropane as raw material | 平顶山学院 | 2025-05-16 | — | — | CN | claimed |
| CN-119504873-A | Three-dimensional framework large-steric-hindrance nitrogen heterocyclic carbene palladium complex and preparation method and application thereof | 中国人民大学 | 2025-02-25 | — | — | CN | claimed |
| US-20250002489-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING ITK VIA UBIQUITIN PROTEOSOME PATHWAY | NURIX THERAPEUTICS, INC. | 2025-01-02 | — | — | US | claimed |
| CN-118854309-A | Electrochemical mediated reaction method for ring-opening defluorination and hydrogenation of geminal difluoro cyclopropane | 南京林业大学 | 2024-10-29 | — | — | CN | claimed |
| EP-4419520-A2 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING ITK VIA UBIQUITIN PROTEOSOME PATHWAY | Nurix Therapeutics, Inc. (US) | 2024-08-28 | — | — | EP | claimed |
| US-20240279202-A1 | COMPOUNDS FOR INHIBITING OR DEGRADING ITK, COMPOSITIONS, COMPRISING THE SAME METHODS OF THEIR MAKING AND METHODS OF THEIR USE | NURIX THERAPEUTICS, INC. | 2024-08-22 | — | — | US | claimed |
| CN-118292192-A | Composite nanofiber membrane, preparation method thereof and application thereof in agricultural pest control | 华南农业大学 | 2024-07-05 | — | — | CN | claimed |
| CN-117693502-A | Compounds for inhibiting or degrading ITK, compositions comprising the same, methods of making the same, and methods of using the same | 纽力克斯治疗公司 | 2024-03-12 | — | — | CN | claimed |
| CN-117466717-A | Fully substituted alkyl alkenyl ether, preparation method and application | 四川大学 | 2024-01-30 | — | — | CN | claimed |
| US-20230416205-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | TENVIE THERAPEUTICS, INC. | 2023-12-28 | — | — | US | claimed |
| WO-2017216507-A1 | COMPOUNDS | THE UNIVERSITY OF WARWICK (GB) | 2017-12-21 | — | — | WO | claimed |
| EP-2522648-B1 | PROCESS FOR PRODUCING DIFLUOROCYCLOPROPANE COMPOUND | CENTRAL GLASS CO LTD (JP) | 2017-05-17 | — | — | EP | claimed |
| US-8729320-B2 | Method for producing difluorocyclopropane compound | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-05-20 | — | — | US | claimed |
| EP-2522648-A1 | PROCESS FOR PRODUCING DIFLUOROCYCLOPROPANE COMPOUND | Central Glass Company, Limited (JP) | 2012-11-14 | — | — | EP | claimed |
| US-20120277458-A1 | METHOD FOR PRODUCING DIFLUOROCYCLOPROPANE COMPOUND | CENTRAL GLASS COMPANY, LIMITED (JP) | 2012-11-01 | — | — | US | claimed |
| WO-2008071985-A2 | EXTRACTION PROCESS AND PURIFICATION PROCESS | INEOS FLUOR HOLDINGS LIMITED (GB) | 2008-06-19 | — | — | WO | claimed |
| WO-2007144623-A1 | REFRIGERANT COMPOSITIONS | INEOS FLUOR HOLDINGS LIMITED (GB) | 2007-12-21 | — | — | WO | claimed |
| EP-0595980-A1 | BENZODIAZEPINE DERIVATIVES, COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY | MERCK SHARP & DOHME LTD. (GB) | 1994-05-11 | — | — | EP | claimed |
| WO-1993002078-A1 | BENZODIAZEPINE DERIVATIVES, COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY | MERCK SHARP & DOHME LIMITED (GB) | 1993-02-04 | — | — | WO | claimed |
| US-4701563-A | INSECTICIDE, MITICIDE | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-10-20 | — | — | US | claimed |