Sugi Predict

Sugi Predict / Compounds / SCHEMBL653186

SCHEMBL653186

SCHEMBL653186

CCNC1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EPHX1 P07099 1/20 0.60
▸ ALDH1A1 P00352 2/20 0.52
▸ HPGD P15428 1/20 0.51
▸ L3MBTL1 Q9Y468 2/20 0.51
▸ MAPT P10636 2/20 0.51
▸ NPC1 O15118 1/20 0.51
▸ MAPK1 P28482 1/20 0.51
▸ HTT P42858 1/20 0.51
▸ RAB9A P51151 1/20 0.51
▸ RECQL P46063 1/20 0.49
▸ PTPN2 P17706 1/20 0.48
▸ PTPN1 P18031 1/20 0.48
▸ PTPN6 P29350 1/20 0.48
▸ USP2 O75604 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ EPHX2 P34913 1/20 0.47
▸ KDM4E B2RXH2 2/20 0.47
▸ PKM P14618 1/20 0.47
▸ GPR119 Q8TDV5 5/20 0.46
▸ THRB P10828 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13597298 0.94 EPHX1 (0.62) EPHX1ALDH1A1HPGDL3MBTL1MAPT
SCHEMBL2498330 0.91 EPHX1 (0.54) EPHX1ALDH1A1HPGDL3MBTL1MAPT
SCHEMBL652761 0.91 EPHX1 (0.54) EPHX1ALDH1A1HPGDL3MBTL1MAPT
SCHEMBL3255861 0.91 EPHX1 (0.54) EPHX1ALDH1A1HPGDL3MBTL1MAPT
Hydrochloric Acid SCHEMBL2498984 0.89 EPHX1 (0.52) EPHX1ALDH1A1HPGDL3MBTL1MAPT
SCHEMBL3315489 0.88 EPHX1 (0.57) EPHX1ALDH1A1HPGDL3MBTL1MAPT
SCHEMBL5995659 0.86 EPHX1 (0.58) EPHX1ALDH1A1HPGDL3MBTL1MAPT
SCHEMBL842180 0.85 EPHX1 (0.55) EPHX1ALDH1A1HPGDL3MBTL1MAPT
SCHEMBL12501233 0.84 EPHX1 (0.57) EPHX1ALDH1A1HPGDL3MBTL1MAPT
SCHEMBL3267551 0.84 EPHX1 (0.57) EPHX1ALDH1A1HPGDL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7547789-B2 Process for the preparation of N-(4-piperidinyl)-N-ethyl-phenylacetamides from N-Boc-4-oxopiperidine ASTRAZENECA AB (SE) 2009-06-16 — — US claimed
US-20080214824-A1 Process for the Preparation of N-(4-Piperidinyl)-N-Ethyl-Phenylacetamides from N-Boc-4-Oxopiperidine ASTRAZENECA AB (SE) 2008-09-04 — — US claimed
CN-101080387-A Process for the preparation of N- (4-piperidinyl) -N-ethyl-phenylacetamides from N-tert-butoxycarbonyl-4-oxopiperidine ASTRAZENECA AB (SE) 2007-11-28 — — CN claimed
EP-1828128-A1 PROCESS FOR THE PREPARATION OF N-(4-PIPERIDINYL)-N-ETHYL-PHENYLACETAMIDES FROM N-BOC-4-OXOPIPERIDINE AstraZeneca AB (SE) 2007-09-05 — — EP claimed
WO-2006064221-A1 PROCESS FOR THE PREPARATION OF N- (4-PIPERIDINYL) -N-ETHYL-PHENYLACETAMIDES FROM N-BOC-4-OXOPIPERIDINE ASTRAZENECA AB (SE) 2006-06-22 — — WO claimed
EP-4747243-A1 LIGANDS AND COMPOSITIONS AND METHODS OF USE THEREOF Baylor College of Medicine (US) 2026-05-27 — — EP disclosed
US-12617782-B2 Pyridazinones as PARP7 inhibitors RIBON THERAPEUTICS, INC. (US) 2026-05-05 — — US disclosed
EP-4724435-A1 BIFUNCTIONAL AZINES CONJOGATES AS SELECTIVE DEGRADERS OF SMARCA2 AND THERAPEUTIC USES THEREOF Nurix Therapeutics, Inc. (US) 2026-04-15 — — EP disclosed
EP-4674484-A2 THIENOPYRROLE COMPOUNDS Gilead Sciences, Inc. (US) 2026-01-07 — — EP disclosed
WO-2025242565-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF IN THE PREVENTION OR THERAPY OF DISEASES Samsara Therapeutics Inc. (US) 2025-11-27 — — WO disclosed
EP-4653432-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF IN THE PREVENTION OR THERAPY OF DISEASES Samsara Therapeutics Inc. (US) 2025-11-26 — — EP disclosed
EP-4291562-B1 THIENOPYRROLE COMPOUNDS GILEAD SCIENCES INC (US) 2025-09-10 — — EP disclosed
EP-1220842-A1 CYCLIC AMINE COMPOUNDS AS CCR5 ANTAGONISTS Takeda Chemical Industries, Ltd. (JP) 2002-07-10 — — EP disclosed
US-6399619-B1 PREVENTION AND TREATMENT OF AIDS AND VIRAL INFECTION BY HIV MERCK & CO., INC. 2002-06-04 — — US disclosed
WO-2001025200-A1 CYCLIC AMINE COMPOUNDS AS CCR5 ANTAGONISTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-04-12 — — WO disclosed
CN-1287487-A Aminophenoxyacetic acid derivatives and pharmaceutical compositions containing them SUNTORY LTD (JP) 2001-03-14 — — CN disclosed
EP-1045693-A1 AMINOPHENOXYACETIC ACID DERIVATIVES AS NEUROPROTECTANTS SUNTORY LIMITED (JP) 2000-10-25 — — EP disclosed
WO-2000059498-A1 PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY MERCK & CO., INC. (US) 2000-10-12 — — WO disclosed
WO-2000059497-A1 PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY MERCK & CO., INC. (US) 2000-10-12 — — WO disclosed
WO-2000023076-A1 AMINOPHENOXYACETIC ACID DERIVATIVES AS NEUROPROTECTANTS SUNTORY LIMITED (JP) 2000-04-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617782-B2 Pyridazinones as PARP7 inhibitors PARP3, PARP2, PARP1 EPHX1 2674/4885ALDH1A1 686/4885HPGD 668/4885
US-20080214824-A1 Process for the Preparation of N-(4-Piperidinyl)-N-Ethyl-Phenylacetamides from N-Boc-4-Oxopiperidine NISCH, NPPA, AZI2 EPHX1 400/4885ALDH1A1 1195/4885HPGD 887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.