SCHEMBL6532060

SCHEMBL6532060

NCC(Cc1ccc(-c2ccccc2)cc1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.60
SRR Q9GZT4 2/20 0.58
PSAT1 Q9Y617 2/20 0.58
MME P08473 8/20 0.54
ACE P12821 2/20 0.54
CPA1 P15085 2/20 0.53
CPA3 P15088 2/20 0.53
FOLH1 Q04609 1/20 0.53
CPB1 P15086 1/20 0.53
CPB2 Q96IY4 1/20 0.53
SLC1A3 P43003 1/20 0.53
SLC1A2 P43004 1/20 0.53
SLC1A1 P43005 1/20 0.53
PPARG P37231 2/20 0.53
PPARA Q07869 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5171909 0.89 CYP1A2 (0.76) CYP1A2MMECPA1CPA3FOLH1
SCHEMBL4738634 0.89 CYP1A2 (0.76) CYP1A2MMECPA1CPA3FOLH1
SCHEMBL558159 0.89 CYP1A2 (0.76) CYP1A2MMECPA1CPA3FOLH1
Hydrochloric Acid SCHEMBL23699291 0.87 CYP1A2 (0.73) CYP1A2SRRMMECPA1CPA3
SCHEMBL4738660 0.81 SLC7A5 (0.61) CYP1A2MMECPA1CPA3FOLH1
SCHEMBL4620825 0.81 SLC7A5 (0.61) CYP1A2MMECPA1CPA3FOLH1
SCHEMBL26076534 0.81 PPARG (0.59) CYP1A2CPA1CPA3FOLH1SLC1A3
Ethyl Chloride SCHEMBL1185929 0.81 CYP1A2 (0.63) CYP1A2MMECPA1CPA3FOLH1
SCHEMBL4619838 0.80 CYP1A2 (0.52) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL21193997 0.80 CYP1A2 (0.52) CYP1A2MMEACECPA1CPA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005030735-A1 TRIAZINES DERIVATIVES AS CELL ADHESION INHIBITORS RANBAXY LABORATORIES LIMITED (IN) 2005-04-07 WO claimed