Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ANPEP | P15144 | 3/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.49 |
| ▸ | LAP3 | P28838 | 1/20 | 0.49 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 2/20 | 0.47 |
| ▸ | CPA3 | P15088 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738660 | 1.00 | SLC7A5 (0.61) | SLC7A5CYP1A2ANPEPERAP2ERAP1 | |
| SCHEMBL10436391 | 0.88 | CYP1A2 (0.68) | SLC7A5CYP1A2ANPEPERAP2ERAP1 | |
| SCHEMBL28035896 | 0.85 | SLC7A5 (0.58) | SLC7A5CYP1A2ANPEPERAP2ERAP1 | |
| SCHEMBL4738634 | 0.84 | CYP1A2 (0.76) | SLC7A5CYP1A2ANPEPERAP2SLC1A3 | |
| SCHEMBL5171909 | 0.84 | CYP1A2 (0.76) | SLC7A5CYP1A2ANPEPERAP2SLC1A3 | |
| SCHEMBL558159 | 0.84 | CYP1A2 (0.76) | SLC7A5CYP1A2ANPEPERAP2SLC1A3 | |
| SCHEMBL12528500 | 0.84 | SLC7A5 (0.60) | SLC7A5CYP1A2ANPEPERAP2ERAP1 | |
| SCHEMBL12494638 | 0.84 | SLC7A5 (0.60) | SLC7A5CYP1A2ANPEPERAP2ERAP1 | |
| SCHEMBL4990096 | 0.83 | SLC7A5 (0.51) | SLC7A5CYP1A2ANPEPERAP2ERAP1 | |
| SCHEMBL21193997 | 0.83 | CYP1A2 (0.52) | CYP1A2ANPEPERAP2SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883620-A1 | ß-AMINO ACID DERIVATIVES | Pfizer Limited (GB) | 2008-02-06 | — | — | EP | claimed |
| WO-2006120544-A1 | β-AMINO ACID DERIVATIVES | PFIZER LIMITED (GB) | 2006-11-16 | — | — | WO | claimed |
| US-20150191459-A1 | CATHEPSIN INHIBITORS | VIROBAY, INC. | 2015-07-09 | — | — | US | disclosed |
| US-20140256698-A1 | CATHEPSIN INHIBITORS | VIROBAY, INC. | 2014-09-11 | — | — | US | disclosed |
| EP-1883620-A1 | ß-AMINO ACID DERIVATIVES | Pfizer Limited (GB) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006120544-A1 | β-AMINO ACID DERIVATIVES | PFIZER LIMITED (GB) | 2006-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191459-A1 | CATHEPSIN INHIBITORS | CTSF, CTSZ, CTSV | SLC7A5 1448/4885CYP1A2 4403/4885ANPEP 46/4885 |
| US-20140256698-A1 | CATHEPSIN INHIBITORS | CTSF, CTSZ, CTSV | SLC7A5 1448/4885CYP1A2 4403/4885ANPEP 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.